Vidal Garate J, Romero-Ayala L C, Cárdenas Loaeza M
Arch Inst Cardiol Mex. 1983 Mar-Apr;53(2):159-78.
In this paper some of the new antiarrhythmic drugs are reviewed. The origin, electrophysiologic effects, mechanisms of action, pharmacokinetic properties, hemodynamic changes, clinical utilization with indications and contraindications as well as the collateral effects of: Verapamil Amiodarone, Aprindine, Encainide, Mexiletine and Tocainide are analyzed. A conclusion is drawn for each one of these drugs in accordance with the available information in the literature and the author's criteria and experience.
本文对一些新型抗心律失常药物进行了综述。分析了维拉帕米、胺碘酮、阿普林定、恩卡胺、美西律和妥卡尼的起源、电生理效应、作用机制、药代动力学特性、血流动力学变化、临床应用(包括适应证和禁忌证)以及副作用。根据文献中的现有信息以及作者的标准和经验,对这些药物中的每一种都得出了结论。