利纳亚病毒的特征：与布尼亚病毒的相似性。

Characterization of Leanyer virus: resemblance to Bunyavirus.

作者信息

Stuckly K G, Wright P J

出版信息

Aust J Exp Biol Med Sci. 1983 Apr;61 (Pt 2):193-200. doi: 10.1038/icb.1983.18.

DOI:10.1038/icb.1983.18

Abstract

The properties of Leanyer virus, isolated in Northern Australia in 1974, were compared with those of Bunyamwera virus. Leanyer virus replicated in BHK-21 and Vero cells. In sucrose gradients it had a density of 1.17 g/cm3 and sedimented with the same s value as Bunyamwera virus. The diameter of negatively stained virions was approximately 110 nm. Three species of RNA sedimenting at 30S (L), 26S (M) and 14S (S) and four virion proteins (L, G1, G2, N) were detected in preparations of purified virions. The results were consistent with the classification of Leanyer virus as a member of the family Bunyaviridae, possibly within the Bunyavirus genus.

摘要

1974年在澳大利亚北部分离出的利纳耶尔病毒的特性与布尼亚姆韦拉病毒的特性进行了比较。利纳耶尔病毒能在BHK - 21和Vero细胞中复制。在蔗糖梯度中，它的密度为1.17 g/cm³，沉降系数与布尼亚姆韦拉病毒相同。经负染的病毒粒子直径约为110纳米。在纯化的病毒粒子制剂中检测到三种沉降系数分别为30S（L）、26S（M）和14S（S）的RNA以及四种病毒粒子蛋白（L、G1、G2、N）。结果表明，利纳耶尔病毒符合布尼亚病毒科成员的分类，可能属于布尼亚病毒属。