Dutar P, Lamour Y, Jobert A
C R Seances Acad Sci III. 1983;296(19):927-30.
Two groups of neurons which are excited by the iontophoretic application of acetylcholine were described in the primary somatosensory cortex of the Rat. The first one is located in the middle part (group A) and the second one in the deepest part of the cortex (group B). Group A neurons had a higher average spontaneous activity than group B neurons. The latency of group A neurons responses to the iontophoretic application of acetylcholine was longer. The amount of iontophoretic current required to increase the discharge rate of the neuron by 200% was higher in group A than in group B. In contrast the average slope of the regression lines calculated from dose-response curves was not different between the two groups.
在大鼠的初级体感皮层中，发现了两组可被离子电渗法施加乙酰胆碱激活的神经元。第一组位于皮层中部（A组），第二组位于皮层最深层（B组）。A组神经元的平均自发活动高于B组神经元。A组神经元对离子电渗法施加乙酰胆碱的反应潜伏期更长。将神经元放电率提高200%所需的离子电渗电流强度，A组高于B组。相比之下，根据剂量-反应曲线计算出的回归线平均斜率在两组之间并无差异。
