Labeyrie E, Murphy W, Behar A, Baillet J
C R Seances Acad Sci III. 1983;296(21):1009-12.
The application of a venous tourniquet leads to distension of the distal venous and capillary circulation and a local increase in plasma volume. In the normal subject, plasma volume returns to its initial level within approximately 10 sec of tourniquet release. In subjects affected by cyclical oedema, the local increase in plasma volume persists several minutes after tournique release. Radioactive labelling of plasma proteins shows that this delay is associated with the retention of plasma proteins by the tissues. These proteins are subsequently cleared by lymphatic drainage or diffusion back into veins. These results suggest that the combination of tournique test with the labelling of plasma proteins measures capillary and venous permeability as well as tissue protein clearance kinetics.
使用静脉止血带会导致远端静脉和毛细血管循环扩张，局部血浆量增加。在正常受试者中，止血带松开后约10秒内血浆量会恢复到初始水平。在患有周期性水肿的受试者中，血浆量的局部增加在止血带松开后会持续几分钟。血浆蛋白的放射性标记显示，这种延迟与组织对血浆蛋白的潴留有关。这些蛋白质随后通过淋巴引流或扩散回静脉而被清除。这些结果表明，止血带试验与血浆蛋白标记相结合可测量毛细血管和静脉通透性以及组织蛋白清除动力学。
