Pavel S, Matous B, Duchon J
J Invest Dermatol. 1978 Apr;70(4):197-9. doi: 10.1111/1523-1747.ep12541320.
A simple screening test for estimation of some phenolic and indolic compounds in urine is described. The method is rapid, simple and able to detect all the indolic and phenolic compounds observed, including o-dihydroxy compounds. The method is based on the color reaction with reagent solution composed of sodium tungstate, trichloroacetic acid, hydrochloric acid and sodium nitrite. After alkalinization by sodium hydroxide the optical density is measured at 405 and 490 nm. The latter is specific for o-dihydroxy compounds. This test seems to be useful for estimation of phenolic and indolic compounds in urine of patients with increased production of compounds of this nature, particularly in some tumors.
本文描述了一种用于估算尿液中某些酚类和吲哚类化合物的简单筛查试验。该方法快速、简便，能够检测到所有观察到的吲哚类和酚类化合物，包括邻二羟基化合物。该方法基于与由钨酸钠、三氯乙酸、盐酸和亚硝酸钠组成的试剂溶液的显色反应。用氢氧化钠碱化后，在405和490nm处测量光密度。后者对邻二羟基化合物具有特异性。该试验似乎有助于估算此类化合物生成增加的患者尿液中的酚类和吲哚类化合物，特别是在某些肿瘤患者中。
