Shirey R S, Smith B, Sensenbrenner L, Bauer T W, Ness P M, Kickler T S, Gibble J W
Transfusion. 1983 Sep-Oct;23(5):396-7. doi: 10.1046/j.1537-2995.1983.23584018718.x.
Four Rh-positive patients with severe aplastic anemia received equine anti-lymphocyte globulin. Each developed a positive direct antiglobulin test. Anti-D was identified in eluates prepared from the patients' sensitized red cells. The administered lot of anti-lymphocyte globulin was found to contain anti-D. Red cell sensitization due to passively acquired Rh antibodies can result from the administration of anti-lymphocyte globulin.
四名患有严重再生障碍性贫血的Rh阳性患者接受了马抗淋巴细胞球蛋白治疗。每位患者的直接抗球蛋白试验均呈阳性。从患者致敏红细胞制备的洗脱液中鉴定出了抗-D。发现所使用批次的抗淋巴细胞球蛋白含有抗-D。因被动获得性Rh抗体导致的红细胞致敏可能是由于抗淋巴细胞球蛋白的使用引起的。
