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[人皮肤肿瘤非组蛋白染色体蛋白的免疫扩散]

[Immunodiffusion of non-histone chromosomal proteins from human skin tumors].

作者信息

Landi F L, Tirone P, Filippetti R, Olivetti G, Garcovich A

出版信息

Boll Soc Ital Biol Sper. 1983 Aug 30;59(8):1086-8.

PMID:6414491
Abstract

A previously unpublished reaction of precipitation in agarose between histone and non-histone proteins extracted in saline buffer from nuclei of human skin tumors, is reported. Two bands of precipitation similar to those in an immunodiffusion reaction between NHP and specific antisera, were observed. The reaction described is very similar to the affinodiffusion reaction of glycoproteins and lectins in agarose.

摘要

据报道,从人皮肤肿瘤细胞核中用盐缓冲液提取的组蛋白和非组蛋白之间在琼脂糖中发生了一种以前未发表的沉淀反应。观察到两条沉淀带,类似于非组蛋白与特异性抗血清之间免疫扩散反应中的沉淀带。所描述的反应与琼脂糖中糖蛋白和凝集素的亲和扩散反应非常相似。

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