6小时内对黄蜂毒液进行减敏治疗。
Hyposensitisation to wasp venom in six hours.
作者信息
van der Zwan J C, Flinterman J, Jankowski I G, Kerckhaert J A
出版信息
Br Med J (Clin Res Ed). 1983 Nov 5;287(6402):1329-31. doi: 10.1136/bmj.287.6402.1329.
Abstract
Eleven patients with a history of anaphylaxis, positive reactions to skin tests, and specific IgE antibody to wasp venom underwent hyposensitisation in a six hour procedure. No general reactions occurred. Complement activation and proteinuria could not be shown. The patterns of specific IgE, IgG1, and IgG4 were as described in other procedures--namely, IgE increased sharply and then decreased; IgG1 and IgG4 increased steadily and then decreased--but increase and decrease came earlier. Challenge by a stinging insect at least four weeks after treatment proved complete protection. The skin reactivity two years later showed an unpredictable pattern.
摘要
11名有过敏反应病史、皮肤试验呈阳性反应且对黄蜂毒液有特异性IgE抗体的患者在一个6小时的程序中接受了减敏治疗。未发生全身性反应。未显示补体激活和蛋白尿。特异性IgE、IgG1和IgG4的模式与其他程序中所描述的相同——即IgE急剧增加然后下降；IgG1和IgG4稳步增加然后下降——但增加和下降出现得更早。治疗后至少四周受到蜇虫攻击证明有完全的保护作用。两年后的皮肤反应性呈现出不可预测的模式。
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