Wicher V, Wicher K
Br J Vener Dis. 1983 Dec;59(6):359-63. doi: 10.1136/sti.59.6.359.
Samples of serum and testicular fluid from normal rabbits and those infected with Treponema pallidum were examined for total protein, albumin, IgG, and IgM concentrations. Total protein concentrations were similar in testicular fluid from normal and infected animals but were lower than in serum. The concentrations of individual proteins in serum did not differ substantially between infected and non-infected rabbits. In testicular fluid, however, the concentrations of all three proteins, especially IgM, were greater in infected rabbits. A significantly (p less than 0.02) raised testis-IgM index, together with a higher concentration of anti-treponemal IgM in the infected testicular fluid than in autologous serum, suggests local synthesis of IgM antibodies.
对正常兔子以及感染梅毒螺旋体的兔子的血清和睾丸液样本进行了总蛋白、白蛋白、IgG和IgM浓度检测。正常和感染动物的睾丸液中总蛋白浓度相似，但低于血清中的总蛋白浓度。感染和未感染兔子血清中各蛋白质的浓度没有显著差异。然而，在睾丸液中，感染兔子的所有三种蛋白质，尤其是IgM的浓度更高。睾丸-IgM指数显著升高（p小于0.02），且感染的睾丸液中抗梅毒螺旋体IgM的浓度高于自体血清，这表明IgM抗体是局部合成的。
