Determination of clonazepam in tablets by dc polarography.
作者信息
Vinh C T, Braun J, Plourde J R
出版信息
J Pharm Sci. 1978 May;67(5):731-3. doi: 10.1002/jps.2600670551.
PMID:641825
Abstract
A simple and convenient method for the routine determination of clonazepam in tablets by dc polarography is described. Clonazepam is extracted from the sample by ethanol and diluted with pH 4.15 acetate buffer in a volumetric flask. The filtered solution is then polarographed at the dropping mercury electrode versus the saturated calomel electrode. The polarographic wave is well developed; the determination is quantitative, precise, and accurate.
摘要
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