[Proliferation of poorly differentiated cells in the rat liver after a single injection of the hepatocarcinogen 4-dimethylaminoazobenzine and its noncarcinogenic analog].

With the aid of autoradiography, the proliferation of non-differentiated (oval and transitional) cells in rat liver induced by a single injection of hepatocarcinogen 4-dimethylaminoazobenzene and its non-carcinogenic analogue has been studied. These cells are characterized by a high proliferative activity reaching its maximum 4 days after injection of both the agents. Later on, the proliferative activity decreased due probably to differentiation of such cells.