Zakharova N V, Medvedeva N D, Khodosova I A, Ivanov V A, Fel' V Ia
Tsitologiia. 1980 Jul;22(7):800-3.
The localization of a fetal isoenzyme of aldolase (A) in rat liver cells early after a single injection of carcinogen 4-dimethylaminoazobenzene and its noncarcinogenic analog 4-diethylaminoazobenzene has been studied using the immunofluorescent method. Aldolase A was found in the cytoplasm of oval and "transition" cells. These cells appeared in rat liver as a result of treatment with carcinogen and its analog. In mature hepatocytes aldolase A was not found either in intact rat liver, after the treatment with carcinogen or its analog.
采用免疫荧光法研究了单次注射致癌物4-二甲基氨基偶氮苯及其非致癌类似物4-二乙氨基偶氮苯后早期大鼠肝细胞中醛缩酶（A）胎儿同工酶的定位。在卵圆细胞和“过渡”细胞的细胞质中发现了醛缩酶A。这些细胞是在用致癌物及其类似物处理后出现在大鼠肝脏中的。在完整的大鼠肝脏中、用致癌物或其类似物处理后，成熟肝细胞中均未发现醛缩酶A。
