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营养不良儿童唾液中的生化变化。

Biochemical changes in saliva of malnourished children.

作者信息

Agarwal P K, Agarwal K N, Agarwal D K

出版信息

Am J Clin Nutr. 1984 Feb;39(2):181-4. doi: 10.1093/ajcn/39.2.181.

DOI:10.1093/ajcn/39.2.181
PMID:6421141
Abstract

The protein concentration and activity of arginase enzymes in serum and saliva was estimated in a total of 94 children out of which 52 were suffering from protein-energy malnutrition (PEM) and 42 served as controls. The salivary ferritin was also estimated in 41 children (control eight and PEM 33). There was a progressive fall in serum and salivary arginase activity and levels of salivary protein and ferritin with severity of PEM. The salivary ferritin showed very significant fall even in PEM grade I. In PEM grade III the mean ferritin value was 3.28 +/- 0.75 micrograms/L as compared to 169.3 +/- 21.9 micrograms/L for normal children. The changes in salivary protein, arginase activity, and ferritin in PEM may be used in recognizing severity as well as early stage of the disease.

摘要

对总共94名儿童的血清和唾液中的精氨酸酶蛋白浓度及活性进行了评估,其中52名患有蛋白质 - 能量营养不良(PEM),42名作为对照。还对41名儿童(8名对照和33名PEM患者)的唾液铁蛋白进行了评估。随着PEM严重程度的增加,血清和唾液精氨酸酶活性以及唾液蛋白和铁蛋白水平逐渐下降。即使在PEM I级中,唾液铁蛋白也显示出非常显著的下降。在PEM III级中,铁蛋白平均值为3.28±0.75微克/升,而正常儿童为169.3±21.9微克/升。PEM中唾液蛋白、精氨酸酶活性和铁蛋白的变化可用于识别疾病的严重程度以及早期阶段。

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