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生殖支原体和鸡毒支原体中肺炎支原体细胞吸附蛋白P1的缺失。

Absence of Mycoplasma pneumoniae cytadsorption protein P1 in Mycoplasma genitalium and Mycoplasma gallisepticum.

作者信息

Baseman J B, Drouillard D L, Leith D K, Tully J G

出版信息

Infect Immun. 1984 Mar;43(3):1103-5. doi: 10.1128/iai.43.3.1103-1105.1984.

DOI:10.1128/iai.43.3.1103-1105.1984
PMID:6421736
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC264304/
Abstract

Polyclonal and monoclonal antibodies to Mycoplasma pneumoniae protein P1 were nonreactive with whole-cell or soluble preparations of M. genitalium and M. gallisepticum. However, radioimmunoprecipitation performed with hyperimmune rabbit sera raised against each mycoplasma species indicated antigenic cross-reactivity between M. pneumoniae and M. genitalium.

摘要

针对肺炎支原体蛋白P1的多克隆抗体和单克隆抗体与生殖支原体及鸡毒支原体的全细胞制剂或可溶性制剂均无反应。然而，用针对每种支原体产生的超免疫兔血清进行的放射免疫沉淀表明，肺炎支原体与生殖支原体之间存在抗原交叉反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a59c/264304/b7fa20507097/iai00132-0334-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a59c/264304/b4bb5755219d/iai00132-0334-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a59c/264304/b7fa20507097/iai00132-0334-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a59c/264304/b4bb5755219d/iai00132-0334-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a59c/264304/b7fa20507097/iai00132-0334-b.jpg

相似文献

1
Absence of Mycoplasma pneumoniae cytadsorption protein P1 in Mycoplasma genitalium and Mycoplasma gallisepticum.生殖支原体和鸡毒支原体中肺炎支原体细胞吸附蛋白P1的缺失。
Infect Immun. 1984 Mar;43(3):1103-5. doi: 10.1128/iai.43.3.1103-1105.1984.
2
Antigenic determinants of the attachment protein of Mycoplasma pneumoniae shared by other pathogenic Mycoplasma species.肺炎支原体黏附蛋白的抗原决定簇与其他致病性支原体物种共有。
Infect Immun. 1986 Feb;51(2):690-2. doi: 10.1128/iai.51.2.690-692.1986.
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Shared epitopes between Mycoplasma pneumoniae major adhesin protein P1 and a 140-kilodalton protein of Mycoplasma genitalium.肺炎支原体主要黏附蛋白P1与生殖支原体140千道尔顿蛋白之间的共同表位。
Infect Immun. 1987 Jan;55(1):49-56. doi: 10.1128/iai.55.1.49-56.1987.
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A Mycoplasma genitalium protein resembling the Mycoplasma pneumoniae attachment protein.一种类似于肺炎支原体黏附蛋白的生殖支原体蛋白。
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Mycoplasma genitalium and Mycoplasma pneumoniae share a 67 kilodalton protein as a main cross-reactive antigen.生殖支原体和肺炎支原体共有一种67千道尔顿的蛋白质作为主要交叉反应抗原。
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Conservation of pathogenic mycoplasma antigens.致病性支原体抗原的保守性。
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Molecular characterization of Mycoplasma genitalium species-specific and cross-reactive determinants: identification of an immunodominant protein of M. genitalium.生殖支原体物种特异性和交叉反应性决定簇的分子特征：生殖支原体一种免疫显性蛋白的鉴定。
Isr J Med Sci. 1987 May;23(5):453-7.
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Antibodies in the sera of Mycoplasma pneumoniae-infected patients against proteins of Mycoplasma genitalium and other mycoplasmas of man.肺炎支原体感染患者血清中针对生殖支原体及其他人类支原体蛋白质的抗体。
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Adhesion and inhibition assay of Mycoplasma genitalium and M. pneumoniae by immunofluorescence microscopy.通过免疫荧光显微镜对生殖支原体和肺炎支原体进行黏附与抑制试验。
J Med Microbiol. 2002 May;51(5):361-373. doi: 10.1099/0022-1317-51-5-361.

引用本文的文献

1
Isolation and characterization of Mycoplasma genitalium strains from the human respiratory tract.从人类呼吸道分离和鉴定生殖支原体菌株。
J Clin Microbiol. 1988 Nov;26(11):2266-9. doi: 10.1128/jcm.26.11.2266-2269.1988.
2
The principal protein antigens of isolates of Mycoplasma pneumoniae as measured by levels of immunoglobulin G in human serum are stable in strains collected over a 10-year period.通过人血清中免疫球蛋白G水平测定的肺炎支原体分离株的主要蛋白质抗原，在10年期间收集的菌株中是稳定的。
Infect Immun. 1987 Aug;55(8):1830-6. doi: 10.1128/iai.55.8.1830-1836.1987.
3
Reaction pattern of human anti-Mycoplasma pneumoniae antibodies in enzyme-linked immunosorbent assays and immunoblotting.

本文引用的文献

1
Sialic acid residues mediate Mycoplasma pneumoniae attachment to human and sheep erythrocytes.唾液酸残基介导肺炎支原体与人及绵羊红细胞的黏附。
Infect Immun. 1982 Oct;38(1):389-91. doi: 10.1128/iai.38.1.389-391.1982.
2
Molecular basis for cytadsorption of Mycoplasma pneumoniae.肺炎支原体细胞吸附的分子基础。
J Bacteriol. 1982 Sep;151(3):1514-22. doi: 10.1128/jb.151.3.1514-1522.1982.
3
Mycoplasma pneumoniae proteins that selectively bind to host cells.选择性结合宿主细胞的肺炎支原体蛋白。
人抗肺炎支原体抗体在酶联免疫吸附测定和免疫印迹中的反应模式。
J Clin Microbiol. 1986 Mar;23(3):517-22. doi: 10.1128/jcm.23.3.517-522.1986.
4
DNA and protein sequence homologies between the adhesins of Mycoplasma genitalium and Mycoplasma pneumoniae.生殖支原体与肺炎支原体黏附素之间的DNA和蛋白质序列同源性。
Infect Immun. 1989 Apr;57(4):1059-65. doi: 10.1128/iai.57.4.1059-1065.1989.
5
Immunological cross-reactivity of a Mycoplasma pneumoniae membrane-associated protein antigen with Mycoplasma genitalium and Acholeplasma laidlawii.肺炎支原体膜相关蛋白抗原与生殖支原体及莱氏无胆甾原体的免疫交叉反应性。
J Clin Microbiol. 1987 Nov;25(11):2136-9. doi: 10.1128/jcm.25.11.2136-2139.1987.
6
A Mycoplasma genitalium protein resembling the Mycoplasma pneumoniae attachment protein.一种类似于肺炎支原体黏附蛋白的生殖支原体蛋白。
Infect Immun. 1987 May;55(5):1126-31. doi: 10.1128/iai.55.5.1126-1131.1987.
7
Shared epitopes between Mycoplasma pneumoniae major adhesin protein P1 and a 140-kilodalton protein of Mycoplasma genitalium.肺炎支原体主要黏附蛋白P1与生殖支原体140千道尔顿蛋白之间的共同表位。
Infect Immun. 1987 Jan;55(1):49-56. doi: 10.1128/iai.55.1.49-56.1987.
8
Species-specific monoclonal antibody to a 43,000-molecular-weight membrane protein of Mycoplasma pneumoniae.针对肺炎支原体43000分子量膜蛋白的种特异性单克隆抗体。
J Clin Microbiol. 1986 Oct;24(4):680-3. doi: 10.1128/jcm.24.4.680-683.1986.
9
Antigenic determinants of the attachment protein of Mycoplasma pneumoniae shared by other pathogenic Mycoplasma species.肺炎支原体黏附蛋白的抗原决定簇与其他致病性支原体物种共有。
Infect Immun. 1986 Feb;51(2):690-2. doi: 10.1128/iai.51.2.690-692.1986.
Infect Immun. 1982 Jul;37(1):382-6. doi: 10.1128/iai.37.1.382-386.1982.
4
Inhibition of mycoplasma pneumoniae hemadsorption and adherence to respiratory epithelium by antibodies to a membrane protein.抗膜蛋白抗体对肺炎支原体血细胞吸附及黏附于呼吸道上皮的抑制作用。
Infect Immun. 1983 Mar;39(3):1180-6. doi: 10.1128/iai.39.3.1180-1186.1983.
5
Reacquisition of specific proteins confers virulence in Mycoplasma pneumoniae.特定蛋白质的重新获得赋予肺炎支原体毒力。
Infect Immun. 1983 Feb;39(2):830-6. doi: 10.1128/iai.39.2.830-836.1983.
6
Host discrimination of Mycoplasma pneumoniae proteinaceous immunogens.宿主对肺炎支原体蛋白质免疫原的识别。
J Exp Med. 1983 Feb 1;157(2):502-14. doi: 10.1084/jem.157.2.502.
7
An ELISA to detect monoclonal antibodies specific for lipid determinants of Mycoplasma pneumoniae.一种用于检测针对肺炎支原体脂质决定簇的单克隆抗体的酶联免疫吸附测定。
J Immunol Methods. 1983 Nov 11;64(1-2):165-78. doi: 10.1016/0022-1759(83)90395-2.
8
Serological cross-reactions between Mycoplasma genitalium and M. pneumoniae.生殖支原体与肺炎支原体之间的血清学交叉反应。
Lancet. 1983 Mar 5;1(8323):527. doi: 10.1016/s0140-6736(83)92212-2.
9
Serological cross-reactions between "Mycoplasma genitalium" and M. pneumoniae.“生殖支原体”与肺炎支原体之间的血清学交叉反应。
Lancet. 1982 Nov 20;2(8308):1158-9. doi: 10.1016/s0140-6736(82)92809-4.
10
A newly discovered mycoplasma in the human urogenital tract.一种新发现的存在于人类泌尿生殖道中的支原体。
Lancet. 1981 Jun 13;1(8233):1288-91. doi: 10.1016/s0140-6736(81)92461-2.