具有抑制素样活性的人精浆肽的分离、结构与合成
Isolation, structure, and synthesis of a human seminal plasma peptide with inhibin-like activity.
作者信息
Ramasharma K, Sairam M R, Seidah N G, Chrétien M, Manjunath P, Schiller P W, Yamashiro D, Li C H
出版信息
Science. 1984 Mar 16;223(4641):1199-202. doi: 10.1126/science.6422553.
PMID:6422553
Abstract
A basic peptide isolated from pooled human seminal plasma exhibited inhibin-like activity by suppressing pituitary follicle-stimulating hormone secretion in vitro and in vivo. The peptide has been characterized and sequenced, and a 31-amino-acid synthetic replicate showed full biological activity in vitro.
摘要
从人精浆混合物中分离出的一种碱性肽，在体内外均通过抑制垂体促卵泡激素分泌而表现出抑制素样活性。该肽已被鉴定和测序，一种由31个氨基酸组成的合成复制品在体外显示出完全的生物活性。
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