Khitrov N K, Alaverdian A M
Kosm Biol Aviakosm Med. 1978 Mar-Apr;12(2):53-6.
The functional reserves of sympathetic systems, i.e. their capacity to stabilize the level of norepinephrine in the enlarged myocardium of rats exposed to chronic hypoxia, increased with their adaptation to hypoxia and decreased with their deadaptation. The level of these reserves depended at large on the rate of norepinephrine biosynthesis. The degree of myocardial hypertrophy of this genesis increased with prolongation of the hypoxic exposure. It is concluded that optimal supply of norepinephrine to the enlarged heart due to increased functional reserves of sympathetic systems is possible only up to a certain level of an increase in the myocardial mass.
交感神经系统的功能储备，即其在暴露于慢性缺氧的大鼠增大心肌中稳定去甲肾上腺素水平的能力，随着对缺氧的适应而增加，随着脱适应而降低。这些储备水平在很大程度上取决于去甲肾上腺素的生物合成速率。这种类型的心肌肥大程度随着缺氧暴露时间的延长而增加。得出的结论是，由于交感神经系统功能储备增加，向增大心脏提供最佳去甲肾上腺素供应仅在心肌质量增加到一定水平之前才有可能。
