Nuzhnyĭ V P, Alaverdian A M
Fiziol Zh SSSR Im I M Sechenova. 1978 Oct;64(10):1414-8.
Disrupted training of rats for hypoxia during 3 weeks at the normal atmospheric pressure increases their resistance to the profound testing hypoxia. Stability of the noradrenaline (NA) level in conditions of isolated heart perfusion, a decrease in the NA neuronal uptake, and an increasing inhibitory effect of the exogenous NA on the synthesis of dioxyphenylalanine indicate an ample functional reserve in the adrenergic structures of these animals. A longer training (5 weeks) diminishing the resistance of rats to the testing hypoxic influence and entails phenomena of heart deadaptation at the level of its adrenergic structures.
在正常大气压下对大鼠进行为期3周的缺氧训练中断，会增加它们对深度测试性缺氧的抵抗力。在离体心脏灌注条件下去甲肾上腺素（NA）水平的稳定性、NA神经元摄取的减少以及外源性NA对二羟苯丙氨酸合成的抑制作用增强，表明这些动物的肾上腺素能结构具有充足的功能储备。更长时间的训练（5周）会降低大鼠对测试性缺氧影响的抵抗力，并在其肾上腺素能结构水平上引发心脏去适应现象。
