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青霉过敏性肺泡炎：中央供暖系统安装不当。

Penicillium allergic alveolitis: faulty installation of central heating.

作者信息

Fergusson R J, Milne L J, Crompton G K

出版信息

Thorax. 1984 Apr;39(4):294-8. doi: 10.1136/thx.39.4.294.

DOI:10.1136/thx.39.4.294
PMID:6426074
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC459786/
Abstract

A married couple presented with an illness typical of allergic alveolitis. A careful search of their home revealed a leak in the central heating system with a heavy fungal growth on wet flooring and linoleum. Two species of Penicillium, P chrysogenum and P cyclopium, were isolated from floorboards, linoleum, and settle plates. Antibodies against both these fungi were demonstrated in the serum of both patients by an enzyme linked immunosorbent assay (ELISA). Allergic alveolitis caused by P chrysogenum and P cyclopium has not been described previously.

摘要

一对已婚夫妇表现出典型的过敏性肺泡炎症状。对他们家进行仔细检查后发现，中央供暖系统有泄漏，潮湿的地板和油毡上有大量真菌生长。从地板、油毡和沉降平板中分离出两种青霉菌，即产黄青霉和环青霉。通过酶联免疫吸附测定（ELISA）在两名患者的血清中均检测到针对这两种真菌的抗体。此前尚未有关于产黄青霉和环青霉引起过敏性肺泡炎的描述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9904/459786/1c39e9e1c594/thorax00220-0057-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9904/459786/d71ea67b4e96/thorax00220-0055-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9904/459786/85c1d6d5a267/thorax00220-0055-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9904/459786/4b3073f40651/thorax00220-0055-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9904/459786/75a64db1752c/thorax00220-0055-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9904/459786/1c39e9e1c594/thorax00220-0057-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9904/459786/d71ea67b4e96/thorax00220-0055-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9904/459786/85c1d6d5a267/thorax00220-0055-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9904/459786/4b3073f40651/thorax00220-0055-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9904/459786/75a64db1752c/thorax00220-0055-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9904/459786/1c39e9e1c594/thorax00220-0057-a.jpg

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本文引用的文献

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Hypersensitivity pneumonitis induced by Penicillium species.
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Antibodies to pigeon antigens in pigeon breeders. Detection of antibodies by an enzyme-linked immunosorbent assay.鸽饲养者体内针对鸽抗原的抗体。通过酶联免疫吸附测定法检测抗体。
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室内霉菌、产毒真菌与黑曲霉：传染病视角
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[Cheese washer's disease ("Kaesewascherkrankheit"), a special form of farmer's lung syndrome].[奶酪清洗工病（“Kaesewascherkrankheit”），农民肺综合征的一种特殊形式]
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