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1
Degradation of aspartate transcarbamylase in Bacillus subtilis is deficient in rel mutants but is not mediated by guanosine polyphosphates.枯草芽孢杆菌中天冬氨酸转氨甲酰酶的降解在rel突变体中存在缺陷，但不是由鸟苷多聚磷酸介导的。
J Bacteriol. 1984 May;158(2):746-8. doi: 10.1128/jb.158.2.746-748.1984.
2
A new relaxed mutant of Bacillus subtilis.一种新型的枯草芽孢杆菌松弛突变体。
J Bacteriol. 1982 Feb;149(2):635-41. doi: 10.1128/jb.149.2.635-641.1982.
3
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Involvement of the stringent response in degradation of glutamine phosphoribosylpyrophosphate amidotransferase in Bacillus subtilis.枯草芽孢杆菌中严格反应参与谷氨酰胺磷酸核糖焦磷酸酰胺转移酶的降解
J Bacteriol. 1983 Jul;155(1):56-63. doi: 10.1128/jb.155.1.56-63.1983.
5
Studies on the control of development. Synthesis of two highly phosphorylated nucleotides depends on changes in the composition of ribosomes at the beginning of sporulation in Bacillus subtilis.发育控制的研究。两种高度磷酸化核苷酸的合成取决于枯草芽孢杆菌孢子形成开始时核糖体组成的变化。
Eur J Biochem. 1978 Apr 17;85(2):517-28. doi: 10.1111/j.1432-1033.1978.tb12267.x.
6
Aspartate transcarbamylase synthesis ceases prior to inactivation of the enzyme in Bacillus subtilis.在枯草芽孢杆菌中，天冬氨酸转氨甲酰酶的合成在该酶失活之前就停止了。
J Bacteriol. 1978 Sep;135(3):943-51. doi: 10.1128/jb.135.3.943-951.1978.
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Transcriptional inhibition and production of guanosine polyphosphates in Bacillus subtilis.枯草芽孢杆菌中的转录抑制和鸟苷多磷酸的产生
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Evidence that Bacillus subtilis sporulation induced by the stringent response is caused by the decrease in GTP or GDP.有证据表明，由严紧反应诱导的枯草芽孢杆菌孢子形成是由GTP或GDP的减少引起的。
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[Role of spot gene product in the degradation of pppGpp in bacteria].[斑点基因产物在细菌中pppGpp降解中的作用]
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Accumulation of relA gene-independent ppGpp in Bacillus subtilis vegetative cells upon temperature shift-down.枯草芽孢杆菌营养细胞在温度下降时relA基因非依赖性ppGpp的积累
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引用本文的文献

1
Discoveries in bacterial nucleotide metabolism.细菌核苷酸代谢的发现。
J Biol Chem. 2009 Mar 13;284(11):6585-94. doi: 10.1074/jbc.X800012200. Epub 2008 Oct 23.

本文引用的文献

1
Guanosine-5'-diphosphate-3'-diphosphate (ppGpp) and the regulation of protein breakdown in Escherichia coli.鸟苷-5'-二磷酸-3'-二磷酸（ppGpp）与大肠杆菌中蛋白质降解的调控
J Biol Chem. 1980 Feb 10;255(3):1008-14.
2
Involvement of the stringent response in degradation of glutamine phosphoribosylpyrophosphate amidotransferase in Bacillus subtilis.枯草芽孢杆菌中严格反应参与谷氨酰胺磷酸核糖焦磷酸酰胺转移酶的降解
J Bacteriol. 1983 Jul;155(1):56-63. doi: 10.1128/jb.155.1.56-63.1983.
3
Degradation of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase in vivo.
J Biol Chem. 1983 Mar 10;258(5):2843-51.
4
Nutritional regulation of degradation of aspartate transcarbamylase and of bulk protein in exponentially growing Bacillus subtilis cells.指数生长的枯草芽孢杆菌细胞中天冬氨酸转氨甲酰酶及大量蛋白质降解的营养调控
J Bacteriol. 1983 Jan;153(1):253-8. doi: 10.1128/jb.153.1.253-258.1983.
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Genetics and physiology of the rel system of Bacillus subtilis.枯草芽孢杆菌rel系统的遗传学与生理学
Mol Gen Genet. 1980;178(2):271-9. doi: 10.1007/BF00270472.
6
Stringent response of Bacillus stearothermophilus: evidence for the existence of two distinct guanosine 3',5'-polyphosphate synthetases.嗜热脂肪芽孢杆菌的严谨反应：存在两种不同的鸟苷3',5'-多聚磷酸合成酶的证据
J Bacteriol. 1981 Jan;145(1):68-73. doi: 10.1128/jb.145.1.68-73.1981.
7
Isolation and characterization of an RNA relaxed mutant of B. subtilis.枯草芽孢杆菌RNA松弛突变体的分离与鉴定
Biochem Biophys Res Commun. 1972 Jan 31;46(2):583-8. doi: 10.1016/s0006-291x(72)80179-7.
8
Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Escherichia coli by pseudomonic acid.假单胞菌酸对大肠杆菌异亮氨酰 - 转移核糖核酸合成酶的抑制作用
Biochem J. 1978 Oct 15;176(1):305-18. doi: 10.1042/bj1760305.
9
Further evidence for the involvement of charged tRNA and guanosine tetraphosphate in the control of protein degradation in Escherichia coli.关于带电tRNA和四磷酸鸟苷参与大肠杆菌蛋白质降解调控的进一步证据。
J Biol Chem. 1978 Jun 10;253(11):3945-51.
10
Regulation of bacterial ppGpp and pppGpp.细菌中鸟苷四磷酸（ppGpp）和鸟苷五磷酸（pppGpp）的调控
Annu Rev Microbiol. 1975;29:301-18. doi: 10.1146/annurev.mi.29.100175.001505.

枯草芽孢杆菌中天冬氨酸转氨甲酰酶的降解在rel突变体中存在缺陷，但不是由鸟苷多聚磷酸介导的。

Degradation of aspartate transcarbamylase in Bacillus subtilis is deficient in rel mutants but is not mediated by guanosine polyphosphates.

作者信息

Bond R W, Switzer R L

出版信息

J Bacteriol. 1984 May;158(2):746-8. doi: 10.1128/jb.158.2.746-748.1984.

DOI:10.1128/jb.158.2.746-748.1984
PMID:6427186
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC215496/
Abstract

Degradation of aspartate transcarbamylase in growing and starved Bacillus subtilis was deficient in relA and relC mutants, but these effects were not correlated with differences in the intracellular level of guanosine polyphosphates.

摘要

在生长和饥饿状态的枯草芽孢杆菌中，天冬氨酸转氨甲酰酶的降解在relA和relC突变体中存在缺陷，但这些效应与鸟苷多磷酸的细胞内水平差异无关。