Price V L, Brown L R
J Bacteriol. 1981 Sep;147(3):752-6. doi: 10.1128/jb.147.3.752-756.1981.
When exponentially growing cells of Bacillus subtilis were treated with rifampin or lipiarmycin, both inhibitors of the initiation of ribonucleic acid synthesis, large amounts of (p)ppGpp accumulated. This accumulation appears to be independent of the ribosome-dependent stringent factor reaction because both relA and relC mutants responded in a manner similar to that of the wild type. The possibility that ribonucleic acid polymerase is directly involved in (p)ppGpp metabolism is discussed.
当用利福平或硫链丝菌素（两种核糖核酸合成起始抑制剂）处理枯草芽孢杆菌的指数生长细胞时，大量的（p）ppGpp积累。这种积累似乎独立于核糖体依赖性严谨因子反应，因为relA和relC突变体的反应方式与野生型相似。文中讨论了核糖核酸聚合酶直接参与（p）ppGpp代谢的可能性。
