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主动脉手术中避免同种输血:自体输血、血液稀释及手术技术的作用

Avoidance of homologous transfusion in aortic operations: the role of autotransfusion, hemodilution, and surgical technique.

作者信息

Cutler B S

出版信息

Surgery. 1984 Jun;95(6):717-23.

PMID:6427961
Abstract

The transfusion requirement for 138 aortic reconstructive procedures was minimized through the combined use of hemodilution, autotransfusion, and surgical techniques reported to reduce operative blood loss. Elective procedures required an average of 1.65 U and ruptured aneurysms 9.63 U of homologous blood. Transfusion was avoided altogether in 42.6% of elective reconstructions and 8.3% of emergency procedures. Autotransfusion saved only 1.54 U for elective operations and 0.87 U for ruptured aneurysm, probably because of the effectiveness of hemodilution and specific surgical techniques that minimized dissection and consequent blood loss. Nonetheless, it proved to be cost effective, saving an average of $260 per patient in charges for homologous blood. The combined use of multiple blood conservation methods was shown to substantially reduce the need for homologous transfusion (compared to reported figures for blood use in aortic operations) and adds a measure of increased safety for the patient undergoing aortic operation.

摘要

通过联合使用血液稀释、自体输血以及据报道可减少手术失血的外科技术,138例主动脉重建手术的输血需求降至最低。择期手术平均需要1.65单位的同源血,而破裂性动脉瘤手术则需要9.63单位。在42.6%的择期重建手术和8.3%的急诊手术中完全避免了输血。自体输血在择期手术中仅节省了1.54单位,在破裂性动脉瘤手术中节省了0.87单位,这可能是由于血液稀释的有效性以及特定的外科技术最大限度地减少了解剖操作及随之而来的失血。尽管如此,事实证明它具有成本效益,平均为每位患者节省了260美元的同源血费用。多种血液保护方法联合使用可显著减少对同源输血的需求(与报道的主动脉手术用血数据相比),并为接受主动脉手术的患者增加了一定程度的安全性。

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