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影响黑腹果蝇核糖体RNA顺反子不均衡复制的因素

Factors influencing disproportionate replication of the ribosomal RNA cistrons in Drosophila melanogaster.

作者信息

Dutton F L, Krider H M

出版信息

Genetics. 1984 Jul;107(3):395-404. doi: 10.1093/genetics/107.3.395.

Abstract

This report describes studies of the compensatory response employing D. melanogaster stocks that bear cloned-X chromosomes derived from laboratory populations of strains Oregon R and Canton S. We find that modification of the autosomal background in either the female or the XY male parent influences the expression of the compensatory response by X chromosomes derived from the Canton S population, whereas Oregon R isolates are unresponsive to these effects. We have also studied compensatory replication in X/O larvae produced from cloned-X derivatives of both Canton S and Oregon R. Canton S larval compensation exceeds that of the adult, whereas in Oregon R the converse is true. We have concluded that both X chromosomal and autosomal factors affect the expression and magnitude of the compensatory response.

摘要

本报告描述了利用携带源自俄勒冈R和广东S品系实验室群体的克隆X染色体的黑腹果蝇品系进行的补偿反应研究。我们发现,雌性或XY雄性亲本中常染色体背景的改变会影响源自广东S群体的X染色体的补偿反应表达,而俄勒冈R分离株对这些影响无反应。我们还研究了由广东S和俄勒冈R的克隆X衍生物产生的X/O幼虫中的补偿复制。广东S幼虫的补偿超过成虫,而在俄勒冈R中情况则相反。我们得出结论,X染色体和常染色体因素都会影响补偿反应的表达和程度。

相似文献

10
On ribosomal gene compensation in Drosophila.关于果蝇核糖体基因补偿作用
Cell. 1980 Nov;22(1 Pt 1):149-55. doi: 10.1016/0092-8674(80)90163-4.

本文引用的文献

3
On ribosomal gene compensation in Drosophila.关于果蝇核糖体基因补偿作用
Cell. 1980 Nov;22(1 Pt 1):149-55. doi: 10.1016/0092-8674(80)90163-4.

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