Tartof K D
Science. 1971 Jan 22;171(3968):294-7. doi: 10.1126/science.171.3968.294.
In wild-type Drosophila melanogaster females there are about 250 ribosomal RNA genes in each nucleolus organizer region of the two X chromosomes. When this same nucleolus organizer region is present in flies in only a single dose, the number of ribosomal RNA genes increases to approximately 400. This increase is most easily explained by disproportionate replication of these genes.
在野生型黑腹果蝇雌性个体中,两条X染色体的每个核仁组织区大约有250个核糖体RNA基因。当这个相同的核仁组织区在果蝇中仅以单剂量存在时,核糖体RNA基因的数量增加到大约400个。这种增加最容易用这些基因的不均衡复制来解释。