de Albornoz M B, Villanueva E, de Torres E D
Mycopathologia. 1984 Apr 15;85(3):177-83. doi: 10.1007/BF00440950.
Sporotrichosis is a mycosis which in our country has been described as only producing cutaneous and subcutaneous infections; in other countries it has been reported as causing pulmonary, bone, joint and meningeal infections. Possibly the systemic form also occurs in Venezuela since, along with the causative agent, all other factors considered as predisposing to systemic infection exist here. Through immunodiffusion (ID) and immunoelectrophoresis (IEP) and using a filamentous form metabolic antigen from Sporothrix schenckii, we were able to demonstrate precipitating antibodies against this fungus both in patients with cutaneous sporotrichosis, diagnosed by culture of the infecting agent, and in patients with pulmonary lesions. The IEP test showed the presence of an anodic arc which we have called the 'S' arc, which could be one of the specific antigens of S. schenckii.
孢子丝菌病是一种真菌病，在我国它仅被描述为引起皮肤和皮下感染；在其他国家，据报道它还可导致肺部、骨骼、关节和脑膜感染。委内瑞拉可能也存在全身型孢子丝菌病，因为除了病原体之外，所有其他被认为易引发全身感染的因素在这里都存在。通过免疫扩散（ID）和免疫电泳（IEP），并使用申克孢子丝菌的丝状形态代谢抗原，我们能够在通过感染病原体培养确诊的皮肤孢子丝菌病患者以及肺部病变患者中检测到针对这种真菌的沉淀抗体。免疫电泳试验显示存在一条阳极弧，我们将其称为“S”弧，它可能是申克孢子丝菌的特异性抗原之一。
