Pehrson P O, Bengtsson E
Scand J Infect Dis. 1984;16(2):195-8. doi: 10.3109/00365548409087141.
Metronidazole, in a dose of 40 mg/kg body weight in 3 divided doses for 10 days was used to treat 194 patients infected with Entamoeba histolytica. When 166 subjects were checked 1 month after treatment, with 3 stool samples taken on different days, 20 failures were found giving a parasitic cure rate of 88%. A lower-than-expected failure rate was noted in children, immigrants and asymptomatic subjects. No more failures were found in 78 patients who went through an extended follow-up, with examinations after 4 and 10-12 months.
甲硝唑以40毫克/千克体重的剂量分3次服用，持续10天，用于治疗194例感染溶组织内阿米巴的患者。治疗1个月后对166名受试者进行检查，在不同日期采集3份粪便样本，发现20例治疗失败，寄生虫治愈率为88%。在儿童、移民和无症状受试者中观察到失败率低于预期。在78例接受延长随访的患者中，在4个月以及10 - 12个月后进行检查，未发现更多治疗失败的情况。
