马铃薯纺锤块茎类病毒的核苷酸序列与二级结构
Nucleotide sequence and secondary structure of potato spindle tuber viroid.
作者信息
Gross H J, Domdey H, Lossow C, Jank P, Raba M, Alberty H, Sänger H L
出版信息
Nature. 1978 May 18;273(5659):203-8. doi: 10.1038/273203a0.
DOI:10.1038/273203a0
PMID:643081
Abstract
The viroid of the potato spindle tuber disease (PSTV) is a covalently closed ring of 359 ribonucleotides. As a result of intramolecular base pairing, a serial arrangement of double-helical sections and internal loops form a unique rod-like secondary structure. PSTV is the first pathogen of a eukaryotic organism for which the complete molecular structure has been established.
摘要
马铃薯纺锤块茎病（PSTV）类病毒是一个由359个核糖核苷酸组成的共价闭合环。由于分子内碱基配对，双螺旋区段和内环的序列排列形成了独特的棒状二级结构。PSTV是首个其完整分子结构已被确定的真核生物病原体。
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