Hypersensitivity to dietary components in young farm animals: isolation and partial purification of bovine immunoglobulin E.

An antibody of known specificity and active in long (72 hours) latent period passive cutaneous anaphylactic reactions, was isolated and partially purified from bovine serum. This antibody was not associated with immunoglobulins IgG, IgM or IgA. A rabbit antiserum raised against this antibody and used as an immunoabsorbent, successfully recovered skin sensitising antibody from bovine reaginic serum.