Suidan J S, Young B K
Am J Obstet Gynecol. 1984 Sep 1;150(1):33-7. doi: 10.1016/s0002-9378(84)80105-2.
Umbilical arterial lactate, pH, PO2, PCO2, and base deficit were measured at delivery of 468 live-born infants. The correlation between the 1-minute Apgar score and lactate (r = -0.34) was comparable to that between the 1-minute Apgar score and pH (r = 0.30). The multiple correlation coefficient between the 1-minute Apgar score and all five parameters combined (lactate, pH, PO2, PCO2, and base deficit) was 0.36. This was not significantly higher than the simple correlation coefficient for pH alone (0.30). Similar correlation coefficients were noted for the 5-minute Apgar score. The dividing point between normal and pathologic lactate levels was 3.70 mmol/L. A pH less than 7.20 and a lactate level greater than or equal to 3.70 mmol/L had the same sensitivity, specificity, and positive and negative predictive values for low Apgar scores (less than 7). While pH and lactate are equally correlated with fetal outcome, their combination with each other and with other blood gas parameters does not predict outcome better than either pH or lactate alone.
在468例活产婴儿分娩时测量脐动脉乳酸、pH值、氧分压（PO2）、二氧化碳分压（PCO2）和碱缺失。1分钟阿氏评分与乳酸之间的相关性（r = -0.34）与1分钟阿氏评分与pH值之间的相关性（r = 0.30）相当。1分钟阿氏评分与所有五个参数（乳酸、pH值、PO2、PCO2和碱缺失）综合的复相关系数为0.36。这并不显著高于单独pH值的简单相关系数（0.30）。5分钟阿氏评分也有类似的相关系数。正常与病理性乳酸水平的分界点为3.70 mmol/L。pH值小于7.20且乳酸水平大于或等于3.70 mmol/L对于低阿氏评分（小于7分）具有相同的敏感性、特异性以及阳性和阴性预测值。虽然pH值和乳酸与胎儿结局的相关性相同，但它们相互之间以及与其他血气参数的组合并不能比单独的pH值或乳酸更好地预测结局。
