Barron W M
Ann Intern Med. 1984 Nov;101(5):683-91. doi: 10.7326/0003-4819-101-5-683.
Nonobstetric disease requiring surgery may complicate pregnancy and jeopardize maternal and fetal well-being. Surgery may be safely done if the physician is aware of anatomic and physiologic alterations during gestation that necessitate an altered approach to diagnosis and management. Fetal exposure to all diagnostic and therapeutic agents should be minimized, particularly during organogenesis. However, the risk to the fetus of diagnostic irradiation is justifiable when information essential to maternal health is likely to be obtained. Furthermore, the broad range of available antibiotic, analgesic, and anesthetic agents provide the physician with options for treatment that have an acceptable degree of risk to fetal health. Anesthesia and surgery are tolerated considerably better by the fetus than is maternal hypotension, hypoxia, or sepsis. When an operative procedure is urgently or emergently indicated, pregnancy should not delay timely intervention.
需要手术治疗的非产科疾病可能会使妊娠复杂化,并危及母婴健康。如果医生了解妊娠期的解剖和生理变化,从而需要改变诊断和管理方法,手术可以安全进行。应尽量减少胎儿接触所有诊断和治疗药物,尤其是在器官形成期。然而,当可能获得对母亲健康至关重要的信息时,诊断性辐射对胎儿的风险是合理的。此外,广泛可用的抗生素、镇痛药和麻醉药为医生提供了对胎儿健康风险可接受的治疗选择。胎儿对麻醉和手术的耐受性比母亲低血压、缺氧或败血症要好得多。当急需或紧急进行手术时,妊娠不应延误及时干预。