Corbel M J
Dev Biol Stand. 1984;56:55-62.
A series of host-range mutants has been selected for brucella-phage R. Two of these mutants designated R/O and R/C have been used for typing purposes. Phage R/O is lytic for non-smooth strains of Brucella abortus and for B. ovis. It is genetically unstable however and produces mutants lytic for smooth B. obortus and B. suis. Phage R/C is lytic for non-smooth B. abortus and for B. ovis and B. canis. It is much more stable than phages R or R/O and shows little or no lytic activity on smooth Brucella strains. It has been effective in differentiating B. canis from B. suis in tests on a limited number of strains. In their properties, all of the brucella-phages of the R series resemble their parent phage.
已为布鲁氏菌噬菌体R筛选出一系列宿主范围突变体。其中两个突变体命名为R/O和R/C，已用于分型目的。噬菌体R/O可裂解流产布鲁氏菌的非光滑菌株和绵羊布鲁氏菌。然而，它在遗传上不稳定，会产生可裂解光滑型流产布鲁氏菌和猪布鲁氏菌的突变体。噬菌体R/C可裂解非光滑型流产布鲁氏菌、绵羊布鲁氏菌和犬布鲁氏菌。它比噬菌体R或R/O稳定得多，对光滑型布鲁氏菌菌株几乎没有或没有裂解活性。在对有限数量菌株的测试中，它有效地将犬布鲁氏菌与猪布鲁氏菌区分开来。在特性上，R系列的所有布鲁氏菌噬菌体都与其亲本噬菌体相似。
