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[噬菌体TB、Wb、Fi、BK 2和R对不同布鲁氏菌属菌种的裂解效应谱的比较评估]

[Comparative evaluation of the spectrum of lytic effects of bacteriophages TB, Wb, Fi, BK 2 and R on various Brucella species].

作者信息

Taran I F, Zanina V M, Liamkin G I, Tsybin B P, Tikhenko N I

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1983 Feb(2):48-52.

PMID:6837202
Abstract

The lytic activity of Brucella phages TB, Wb, Fi, BK2 and R on various Brucella species has been studied. Phage TB has been found to lyse B. abortus, B. suis and B. neotoma, phage Fi has proved to be no different from phage TB, while phage Wb has shown higher activity in respect of B. suis; phage BK2 has been found to lyse B. abortus and, to a lesser extent, B. suis and B. melitensis; phage R has shown low activity, while splitting out phages capable of lysing B. abortus cultures in the S-form. All these phages multiply well in the corresponding indicator strains grown in Martin's broth. The Brucella cultures isolated from myomorphous rodents in the northern foothills of the Caucasus have been found to be similar to B. suis in respect to their spectrum of phage sensitivity, differing from B. suis only by forming smaller negative colonies in the presence of phage Wb.

摘要

对布鲁氏菌噬菌体TB、Wb、Fi、BK2和R对各种布鲁氏菌属细菌的裂解活性进行了研究。已发现噬菌体TB可裂解流产布鲁氏菌、猪布鲁氏菌和新墨西哥布鲁氏菌,噬菌体Fi与噬菌体TB并无差异,而噬菌体Wb对猪布鲁氏菌表现出更高的活性;已发现噬菌体BK2可裂解流产布鲁氏菌,对猪布鲁氏菌和马尔他布鲁氏菌的裂解程度较低;噬菌体R活性较低,但能释放出可裂解S型流产布鲁氏菌培养物的噬菌体。所有这些噬菌体在马丁肉汤中生长的相应指示菌株中均能良好繁殖。已发现从高加索北部山麓的鼠形啮齿动物中分离出的布鲁氏菌培养物,就其噬菌体敏感性谱而言与猪布鲁氏菌相似,只是在噬菌体Wb存在时形成的阴性菌落较小,这一点与猪布鲁氏菌不同。

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