Korsbäck C, Höckerstedt K
Res Exp Med (Berl). 1984;184(4):243-9. doi: 10.1007/BF01852383.
Vasopressin has been found to significantly decrease tissue pO2 in the gastrointestinal tract and the liver. The aim of this study was to find out whether 60% oxygen ventilation could prevent the tissue hypoxia. Vasopressin was infused i.v. in ten piglets for 60 min. During the first 30 min they were ventilated by room air and for the following 30 min by 60% oxygen, which did not alter the intestinal tissue pO2, but liver pO2 increased to the normal level. The plasma lactate was significantly decreased by 60% oxygen ventilation. The findings in this experimental study suggest that 60% oxygen ventilation is indicated in the clinical use of vasopressin infusion.
已发现血管加压素可显著降低胃肠道和肝脏的组织氧分压。本研究的目的是探究60%氧通气是否能预防组织缺氧。对十头仔猪静脉输注血管加压素60分钟。在最初30分钟内用室内空气通气，在随后30分钟内用60%的氧气通气，这并未改变肠道组织氧分压，但肝脏氧分压升至正常水平。60%氧通气使血浆乳酸显著降低。该实验研究结果表明，在临床输注血管加压素时应采用60%氧通气。
