Korsbäck C
Acta Chir Scand. 1984;150(8):593-7.
Tissue pO2 and pCO2 were measured in the oesophagus, stomach, small and large bowel and liver of piglets before, during and after a 30-min infusion of vasopressin (2.75 mU/kg/min). For registration of the tissue gas tensions a silicone elastomer tube was used as a tonometer. Systemic arterial and portal blood gas analyses were performed. Plasma lactate was estimated. Cardiac output and portal vein and hepatic artery blood flow were registered. Vasopressin infusion caused significant fall in the tissue pO2 and increase in the pCO2 throughout the gastrointestinal tract. The liver pO2 also decreased, but no change in the liver pCO2 was found. Serum lactic acid increased. There seems to be risk of hypoxic lesion in all parts of the gastrointestinal tract during vasopressin infusion.
在仔猪输注血管加压素（2.75 mU/kg/分钟）30分钟之前、期间及之后，测量其食管、胃、小肠、大肠及肝脏的组织氧分压（pO2）和二氧化碳分压（pCO2）。使用硅橡胶弹性体管作为张力计记录组织气体张力。进行体循环动脉和门静脉血气分析。估算血浆乳酸水平。记录心输出量、门静脉及肝动脉血流量。输注血管加压素导致整个胃肠道组织pO2显著下降，pCO2升高。肝脏pO2也降低，但未发现肝脏pCO2有变化。血清乳酸增加。在输注血管加压素期间，胃肠道各部位似乎都存在缺氧损伤的风险。
