Neilson J P, Munjanja S P, Whitfield C R
Br Med J (Clin Res Ed). 1984 Nov 3;289(6453):1179-82. doi: 10.1136/bmj.289.6453.1179.
In the hope of reducing perinatal risks associated with retardation of intrauterine growth a previously described two stage ultrasound screening schedule was evaluated by a controlled trial in 877 women with low risk single pregnancies. The two stages of ultrasound examination were an assessment of gestational age during early pregnancy followed by measurement of length from crown to rump and area of trunk at between 34 and 36 weeks' gestation. The product of crown to rump length and trunk area was calculated. The sensitivity of this schedule in identifying in advance 94% of babies who were small for dates at birth, with 90% specificity, and the speed and simplicity of measurement confirmed the accuracy and feasibility of two stage ultrasonography as a screening procedure. The controlled trial did not, however, show any benefit from its routine application in these low risk pregnancies.
为降低与宫内生长迟缓相关的围产期风险,一项先前描述的两阶段超声筛查方案在877名单胎低风险妊娠女性中通过对照试验进行了评估。超声检查的两个阶段分别是孕早期对孕周的评估,然后是在妊娠34至36周时测量头臀长度和躯干面积。计算头臀长度与躯干面积的乘积。该方案在提前识别94%出生时小于孕周的婴儿方面具有敏感性,特异性为90%,且测量的速度和简便性证实了两阶段超声检查作为一种筛查程序的准确性和可行性。然而,对照试验并未显示在这些低风险妊娠中常规应用该方案有任何益处。