新月柄杆菌运动所需基因的遗传图谱
Genetic mapping of genes required for motility in Caulobacter crescentus.
作者信息
Ely B, Croft R H, Gerardot C J
出版信息
Genetics. 1984 Nov;108(3):523-32. doi: 10.1093/genetics/108.3.523.
Abstract
Mutations in more than 30 genes affect motility in Caulobacter crescentus. We have determined the chromosomal map locations for 27 genes involved in flagellar morphogenesis (fla), three genes involved in flagellar function (mot), and three genes that have a pleiotropic effect on both motility and bacteriophage resistance (ple). Three multigene clusters have been detected at widely separated chromosomal locations, but in addition, there are 12 fla and mot genes that are found at eight additional sites scattered around the C. crescentus chromosome. Thus, there is more scatter of genes involved in flagellar structure and function than has been observed in other bacterial systems.
摘要
30多个基因的突变会影响新月柄杆菌的运动能力。我们已经确定了27个参与鞭毛形态发生的基因（fla）、3个参与鞭毛功能的基因（mot）以及3个对运动能力和噬菌体抗性都有多效性影响的基因（ple）在染色体图谱上的位置。在染色体上广泛分离的位置检测到了三个多基因簇，但此外，在新月柄杆菌染色体周围散布的另外八个位点还发现了12个fla和mot基因。因此，与其他细菌系统相比，参与鞭毛结构和功能的基因分布更为分散。
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本文引用的文献
1
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Genetics. 1977 Nov;87(3):391-9. doi: 10.1093/genetics/87.3.391.
2
BIOLOGICAL PROPERTIES AND CLASSIFICATION OF THE CAULOBACTER GROUP.柄杆菌属的生物学特性与分类
Bacteriol Rev. 1964 Sep;28(3):231-95. doi: 10.1128/br.28.3.231-295.1964.
3
Construction of a genetic map for Caulobacter crescentus.新月柄杆菌遗传图谱的构建。
J Bacteriol. 1982 Mar;149(3):889-96. doi: 10.1128/jb.149.3.889-896.1982.
4
Transposition of Tn7 occurs at a single site on the Caulobacter crescentus chromosome.Tn7转座发生在新月柄杆菌染色体上的单个位点。
J Bacteriol. 1982 Aug;151(2):1056-8. doi: 10.1128/jb.151.2.1056-1058.1982.
5
Transposon mutagenesis in Caulobacter crescentus.新月柄杆菌中的转座子诱变
J Bacteriol. 1982 Feb;149(2):620-5. doi: 10.1128/jb.149.2.620-625.1982.
6
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J Bacteriol. 1981 Jan;145(1):559-72. doi: 10.1128/jb.145.1.559-572.1981.
7
Differentiation in the Caulobacter cell cycle.柄杆菌细胞周期中的分化
Annu Rev Microbiol. 1976;30:377-407. doi: 10.1146/annurev.mi.30.100176.002113.
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