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通过添加左旋三碘甲状腺原氨酸,去甲丙咪嗪无反应者转变为有反应者,甲状腺功能恢复正常。

Normal thyroid function in desipramine nonresponders converted to responders by the addition of L-triiodothyronine.

作者信息

Schwarcz G, Halaris A, Baxter L, Escobar J, Thompson M, Young M

出版信息

Am J Psychiatry. 1984 Dec;141(12):1614-6. doi: 10.1176/ajp.141.12.1614.

DOI:10.1176/ajp.141.12.1614
PMID:6439059
Abstract

The results of complete thyroid function testing were normal in four desipramine nonresponders who were converted to responders by addition of L-triiodothyronine (T3). These findings suggest that the effectiveness of T3 is not due to correction of subtle thyroid deficiencies.

摘要

4例对去甲丙咪嗪无反应的患者在加用左旋三碘甲状腺原氨酸(T3)后转为有反应,其甲状腺功能全套检测结果正常。这些发现提示,T3的有效性并非源于对轻微甲状腺功能不足的纠正。

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Normal thyroid function in desipramine nonresponders converted to responders by the addition of L-triiodothyronine.通过添加左旋三碘甲状腺原氨酸,去甲丙咪嗪无反应者转变为有反应者,甲状腺功能恢复正常。
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Hormone treatment of depression.抑郁症的激素治疗
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[High dose L-thyroxine in therapy refractory depression. Case analysis and catamnesis as quality control].
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Risk of adverse events with the use of augmentation therapy for the treatment of resistant depression.
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Refractory depression: treatment strategies, with particular reference to the thyroid axis.难治性抑郁症:治疗策略,特别涉及甲状腺轴
J Psychiatry Neurosci. 1997 Nov;22(5):327-31.