[Demonstration of the O-demethylation reaction catalyzed by a peroxidase: application to 9-methoxyellipticine].
作者信息
Meunier G, Paoletti C, Meunier B
出版信息
C R Acad Sci III. 1984;299(15):629-32.
PMID:6440666
Abstract
9-methoxy ellipticine, an antitumor compound, is O-demethylated in presence of the system peroxidase-H2O2; this reaction yields the corresponding electrophilic quinone-imine and methanol. This O-demethylation reaction is reported for the first time and might be possibly extended to some other antitumor drugs.
摘要
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