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早产儿耗氧量的测量:使用质谱仪的方法评估

Measurement of oxygen consumption in preterm infants: assessment of a method using a mass spectrometer.

作者信息

Hammarlund K

出版信息

Clin Physiol. 1984 Dec;4(6):519-31. doi: 10.1111/j.1475-097x.1984.tb00137.x.

DOI:10.1111/j.1475-097x.1984.tb00137.x
PMID:6440733
Abstract

A flow-through system for measurement of oxygen consumption (VO2), carbon dioxide (VCO2) and water (VH2O) production using a mass spectrometer for analysis of PO2, PCO2 and PH2O, was assessed with regard to the range expected for very small preterm infants. The technique was tested by burning ethanol, and close correlations were found between the measured and the theoretical VO2 (VCO2 and VH2O) values. Close correlation was also found between the measured and the theoretical VO2 when oxygen in the system was displaced by a gas mixture containing 10% O2 in nitrogen. The VO2 values found in a small number of infants compare well with values published in the literature. During all tests VO2 was also measured using a paramagnetic oxygen analyser. No significant difference in VO2 was found between the theoretical values and the values found with the two different methods or between the two methods, when the infants were studied.

摘要

使用质谱仪分析PO₂、PCO₂和PH₂O来测量耗氧量(VO₂)、二氧化碳(VCO₂)和水生成量(VH₂O)的流通系统,针对极小的早产儿预期范围进行了评估。通过燃烧乙醇对该技术进行了测试,发现测量的VO₂(VCO₂和VH₂O)值与理论值之间存在密切相关性。当系统中的氧气被含10%氧气的氮气混合气体置换时,测量的VO₂与理论VO₂之间也发现了密切相关性。少数婴儿的VO₂值与文献中公布的值比较吻合。在所有测试过程中,也使用顺磁氧分析仪测量VO₂。研究婴儿时,未发现理论值与两种不同方法测得的值之间或两种方法之间的VO₂存在显著差异。

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