Preussner S, Konrad H, Frick G, Nowotny P, Engelmann C, Blast G
Folia Haematol Int Mag Klin Morphol Blutforsch. 1976;103(5):707-14.
Before and after performing a basic therapy with sanocrysin, thromboytic kinetic examinations were carried out in 12 patients suffering from rheumatoid arthritis. The thrombocyte survival time, maximal recovery and thrombocyte turnover were determined. The surface activity values were given in the form of spleen-heart quotients and liver-heart quotients as well as by surplus impulses over these organs. The findings evaluated statistically reveal that even the untreated rheumatoid arthritis will have thrombocytic kinetics deviating from the norm. By influencing RES the gold treatment will lead to an reduction of the enhanced platelet decomposition. The behaviour of single parameters before and after gold therapy are discussed. The examination of thrombocyte kinetic could not identify a damage of thrombopoiesis in the bone-marrow and in the periphery caused by sanocrysin.
在用金诺芬进行基础治疗前后，对12例类风湿性关节炎患者进行了血栓动力学检查。测定了血小板存活时间、最大恢复率和血小板周转率。表面活性值以脾心商和肝心商的形式给出，以及这些器官上的多余脉冲数。经统计学评估的结果显示，即使未经治疗的类风湿性关节炎也会有偏离正常的血小板动力学。通过影响网状内皮系统，金制剂治疗将导致增强的血小板分解减少。讨论了金制剂治疗前后单个参数的变化情况。血小板动力学检查未能发现金诺芬对骨髓和外周血小板生成的损害。
