Georgopoulos N, Eşanu C, Klepsch I, Florea I
Endocrinologie. 1984 Oct-Dec;22(4):269-75.
Sixteen females with pubertary delay of the isolated hypogonadotropic hypogonadism type (mean age 19 years, age range 14-25 years) were studied by radioimmunoassay of LH and FSH. The mean values +/- SE were compared to the values obtained from 10 girls in the B 5 Tanner stage and 15 normal adult women investigated on the 14th and 21st day of their ovarian cycle. Two females were given the LRH decapeptide and LRH-LA tripeptide stimulation test. In one case the daily variations of circulating serum LH and FSH were followed up. The fluctuations found suggest an ovarian rhythm which is present in the normal adult woman.
对16名患有单纯性促性腺激素缺乏性性腺功能减退型青春期延迟的女性（平均年龄19岁，年龄范围14 - 25岁）进行了促黄体生成素（LH）和促卵泡生成素（FSH）的放射免疫测定研究。将其平均值±标准误与10名处于坦纳B5期的女孩以及15名正常成年女性在其月经周期第14天和第21天所测得的值进行比较。对2名女性进行了促性腺激素释放激素（LRH）十肽和LRH - LA三肽刺激试验。对其中1例患者随访了循环血清LH和FSH的每日变化。所发现的波动提示存在正常成年女性体内的卵巢节律。
