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依托咪酯、阿芬太尼和氟哌利多用于剖宫产的全身麻醉。

General anesthesia with etomidate, alfentanil and droperidol for caesarean section.

作者信息

Regaert P, Noorduin H

出版信息

Acta Anaesthesiol Belg. 1984 Sep;35(3):193-200.

PMID:6441435
Abstract

Seventy-two pregnant women, all of them admitted for caesarean section were given etomidate and succinylcholine for induction of anesthesia. Ventilation was done with N2O/O2. Once the baby was delivered, droperidol 5 mg was injected as an anti-emetic and alfentanil 50 micrograms/kg for analgesia. At the same time an alfentanil infusion was started at a rate of 1 microgram/kg/min. The combination of etomidate, N2O/O2 and a muscle relaxant was adequate in all patients until delivery. The alfentanil infusion of 1 microgram/kg/min. appeared to be sufficient in 82% of the patients. The remaining patients needed a temporary increase of the infusion rate, which was able to abolish all stress responses immediately. Cardiovascular parameters remained quite stable, except during the period in which no alfentanil was given. Recovery was fast, patients being alert within a few minutes after surgery. Postoperative vomiting occurred in 2 patients only.

摘要

72名均因剖宫产入院的孕妇接受依托咪酯和琥珀酰胆碱诱导麻醉。采用N2O/O2进行通气。婴儿娩出后,注射5mg氟哌利多作为止吐药,并注射50微克/千克阿芬太尼用于镇痛。同时,以1微克/千克/分钟的速率开始输注阿芬太尼。在所有患者分娩前,依托咪酯、N2O/O2和肌肉松弛剂的联合使用效果良好。1微克/千克/分钟的阿芬太尼输注速率在82%的患者中似乎足够。其余患者需要暂时提高输注速率,这能够立即消除所有应激反应。除了未给予阿芬太尼的时间段外,心血管参数保持相当稳定。恢复很快,患者术后几分钟内就恢复清醒。仅2例患者出现术后呕吐。

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