霉菌蜡肽，一种由蜡样芽孢杆菌产生的新型抗真菌肽抗生素。
Mycocerein, a novel antifungal peptide antibiotic produced by Bacillus cereus.
作者信息
Wakayama S, Ishikawa F, Oishi K
出版信息
Antimicrob Agents Chemother. 1984 Dec;26(6):939-40. doi: 10.1128/AAC.26.6.939.
Abstract
A peptide was obtained from culture filtrates of a bacterium which was newly isolated and tentatively named Bacillus cereus SW. The peptide was composed of Asx, Ser, Glx, Leu, Tyr, Pro, and an unknown amino acid in a ratio of 2:1:1:1:1:1:1, but, unless hydrolyzed with HCI, it was ninhydrin reaction negative. The peptide effectively inhibited the growth of all fungi and yeasts so far examined, whereas it inhibited none of the bacteria tested.
摘要
从一种新分离出的暂定名为蜡样芽孢杆菌SW的细菌的培养滤液中获得了一种肽。该肽由天冬氨酸、丝氨酸、谷氨酰胺、亮氨酸、酪氨酸、脯氨酸和一种未知氨基酸按2:1:1:1:1:1:1的比例组成，但除非用盐酸水解，否则它与茚三酮反应呈阴性。该肽有效抑制了迄今为止所检测的所有真菌和酵母的生长，而对所测试的细菌均无抑制作用。
相似文献
1
Mycocerein, a novel antifungal peptide antibiotic produced by Bacillus cereus.霉菌蜡肽，一种由蜡样芽孢杆菌产生的新型抗真菌肽抗生素。
Antimicrob Agents Chemother. 1984 Dec;26(6):939-40. doi: 10.1128/AAC.26.6.939.
2
[Purification and characterization of a novel antifungal peptide APS-1 produced by Bacillus cereus].[蜡样芽孢杆菌产生的新型抗真菌肽APS-1的纯化与鉴定]
Wei Sheng Wu Xue Bao. 1999 Aug;39(4):344-9.
3
Bacereutin, an antifungal antibiotic isolated from metabolites of Bacillus cereus CHU 130.
Proc Natl Sci Counc Repub China B. 1989 Oct;13(4):258-61.
4
Antifungal activity displayed by cereulide, the emetic toxin produced by Bacillus cereus.蜡样芽胞杆菌产生的呕吐毒素——呕吐毒素的抗真菌活性。
Appl Environ Microbiol. 2011 Apr;77(7):2555-8. doi: 10.1128/AEM.02519-10. Epub 2011 Jan 28.
5
A new peptide antibiotic, alboleutin.一种新的肽类抗生素，白蛋白素。
J Antibiot (Tokyo). 1980 Jul;33(7):758-9. doi: 10.7164/antibiotics.33.758.
6
Isolation and physico-chemical characterization of an antifungal and antibacterial peptide produced by Bacillus licheniformis A12.
Appl Microbiol Biotechnol. 1993 Jul;39(4-5):438-42. doi: 10.1007/BF00205029.
7
Identification of antimicrobial compound, diketopiperazines, from a Bacillus sp. N strain associated with a rhabditid entomopathogenic nematode against major plant pathogenic fungi.从与植物病原真菌拮抗的杆状菌 N 菌株中鉴定出抗菌化合物二酮哌嗪
J Appl Microbiol. 2012 Oct;113(4):914-24. doi: 10.1111/j.1365-2672.2012.05385.x. Epub 2012 Jul 25.
8
Production and isolation of cerexins C and D studies on antibiotics from the genus Bacillus. XVII.蜡样芽孢杆菌属抗生素的研究之十七：蜡样菌素C和D的产生与分离
J Antibiot (Tokyo). 1976 Dec;29(12):1281-5. doi: 10.7164/antibiotics.29.1281.
9
Zwittermicin A-producing strains of Bacillus cereus from diverse soils.从不同土壤中分离出的产氨甲环酸A的蜡样芽孢杆菌菌株。
Appl Environ Microbiol. 1994 Dec;60(12):4404-12. doi: 10.1128/aem.60.12.4404-4412.1994.
10
Azoxybacilin, a novel antifungal agent produced by Bacillus cereus NR2991. Production, isolation and structure elucidation.
J Antibiot (Tokyo). 1994 Jul;47(7):833-5. doi: 10.7164/antibiotics.47.833.
引用本文的文献
1
Biological Control of Damping-Off of Alfalfa Seedlings with Bacillus cereus UW85.利用蜡状芽孢杆菌 UW85 防治苜蓿幼苗猝倒病
Appl Environ Microbiol. 1990 Mar;56(3):713-8. doi: 10.1128/aem.56.3.713-718.1990.
本文引用的文献
1
Mycobacillin, a new antifungal antibiotic produced by B. subtilis.分枝杆菌素，一种由枯草芽孢杆菌产生的新型抗真菌抗生素。
Nature. 1958 Jan 11;181(4602):134-5. doi: 10.1038/181134a0.
2
Studies on subsporin. I. Isolation and characterization of subsporins A, B and C.
J Antibiot (Tokyo). 1969 Oct;22(10):467-72.
3
Wetting of fibrin plate and apparent promotion of fibrinolysis by surfactin, a new bacterial peptidelipid surfactant.纤维蛋白平板的湿润以及表面活性素（一种新型细菌肽脂表面活性剂）对纤维蛋白溶解的明显促进作用。
Experientia. 1968 Nov 15;24(11):1120-1. doi: 10.1007/BF02147796.
4
Gamma-glutamyl and D- or L-peptide linkages in mycobacillin, a cyclic peptide antibiotic.分枝杆菌素（一种环肽抗生素）中的γ-谷氨酰与D-或L-肽键
Biochem J. 1971 Mar;121(5):839-46. doi: 10.1042/bj1210839.
5
Comparative study of in vitro and in vivo drug effects on cell-mediated cytotoxicity.体外和体内药物对细胞介导的细胞毒性作用的比较研究。
Immunology. 1976 Oct;31(4):631-41.
6
[The structure of mycosubtilin, an antibiotic isolated from Bacillus subtilis (author's transl)].[从枯草芽孢杆菌中分离出的一种抗生素——真菌枯草菌素的结构（作者译）]
Eur J Biochem. 1976 Apr 1;63(2):391-8. doi: 10.1111/j.1432-1033.1976.tb10240.x.
7
[The structure of bacillomycin L, an antibiotic from Bacillus subtilis (author's transl)].
Eur J Biochem. 1977 Jul 1;77(1):61-7. doi: 10.1111/j.1432-1033.1977.tb11641.x.
8
Recent chemical studies on people antibiotics from the genus Bacillus.近期对芽孢杆菌属抗生素的化学研究。
Adv Appl Microbiol. 1978;24:187-214. doi: 10.1016/s0065-2164(08)70640-3.
9
The peptide antibiotics of Bacillus: chemistry, biogenesis, and possible functions.芽孢杆菌的肽抗生素：化学、生物合成及可能的功能。
Bacteriol Rev. 1977 Jun;41(2):449-74. doi: 10.1128/br.41.2.449-474.1977.
Zotero 插件