Suppr超能文献

[氧中毒惊厥期大鼠组织中单胺氧化酶和二胺氧化酶的活性]

[Monoamine oxidase and diamine oxidase activity of the tissues of rats in the convulsive phase of oxygen poisoning].

作者信息

Goroshinskaia I A, Khodakova A A, Korobova L N, Frenkel' M L, Nemashkalova L A

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1984(11):20-4.

PMID:6441605
Abstract

Monoamine oxidase type A activity with substrate serotonine and type B with substrate p-nitrophenylethylamine decreases is rats' brain, liver, heart and blood during oxygen convulsions. Substrate specificity of the enzyme type A alters in all tissues studied. Diamine oxidase activity decreases in brain, lungs and liver approximately in 2 times and increases in blood at 48%. Histamine content increases in all tissues in 3-4 times, in blood--in 12 times. The role of observed changes in the mechanism of oxygen intoxication is discussed.

摘要

在氧气惊厥期间,以血清素为底物的A型单胺氧化酶活性以及以对硝基苯乙胺为底物的B型单胺氧化酶活性在大鼠的脑、肝、心脏和血液中均降低。在所有研究的组织中,A型酶的底物特异性发生改变。二胺氧化酶活性在脑、肺和肝脏中大约降低2倍,而在血液中增加48%。组胺含量在所有组织中增加3 - 4倍,在血液中增加12倍。讨论了所观察到的变化在氧中毒机制中的作用。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验