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[S-腺苷-L-高半胱氨酸:1. 对睡眠的影响]

[S-adenosyl-L-homocysteine: 1. Influence on sleep].

作者信息

Fonlupt P, Roche M, Cronenberger L, Pacheco H

出版信息

Can J Physiol Pharmacol. 1980 Feb;58(2):160-6.

PMID:6445773
Abstract

S-Adenosylhomocysteine, 0.1-20 mg/kg, influences the sleep patterns of rat, cat and rabbit by increasing the slow-wave and fast-wave sleep for 6 h. The SAH effects are increased by p-chlorophenylalanine and iproniazid and unchanged by reserpine. SAH effects are correlated with modification of norepinephrine and serotonin metabolism.

摘要

S-腺苷同型半胱氨酸,0.1 - 20毫克/千克,通过增加慢波睡眠和快波睡眠6小时来影响大鼠、猫和兔子的睡眠模式。对氯苯丙氨酸和异烟肼可增强S-腺苷同型半胱氨酸的作用,而利血平则无此作用。S-腺苷同型半胱氨酸的作用与去甲肾上腺素和血清素代谢的改变相关。

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