Ionescu J, Eskenasy A
Morphol Embryol (Bucur). 1980 Apr-Jun;26(2):155-61.
Three cases of eosinophilic granuloma of the lung were histopathologically analyzed on surgical materials (two resections and lung biopsy). The analysis insisted upon the cell components of pulmonary lesions, histiocytic and eosinocytic accumulations involving lobular air spaces, alveolar walls and interlobular areas, and forming bullae by histiocytic enzymic activity and lipid dysmetabolism; the fibrotic evolution of the lesions varied from case to case. The lesional histogenesis is discussed in the light of recent electronmicroscropic, histochemical and immunopathological data, stress being laid upon the local influence on the development of the process.
对3例肺嗜酸性肉芽肿的手术标本（2例肺切除术和1例肺活检）进行了组织病理学分析。分析着重于肺部病变的细胞成分，即组织细胞和嗜酸性粒细胞在小叶气腔、肺泡壁和小叶间区域的积聚，并通过组织细胞的酶活性和脂质代谢紊乱形成大疱；病变的纤维化演变因病例而异。结合最近的电子显微镜、组织化学和免疫病理学数据对病变的组织发生进行了讨论，重点强调了局部因素对病变发展的影响。
