重新冷冻先前已冷冻去甘油化红细胞的效果。
The effect of refreezing previously frozen-deglycerolized red blood cells.
作者信息
Kahn R A, Auster M, Miller W V
出版信息
Transfusion. 1978 Mar-Apr;18(2):204-5. doi: 10.1046/j.1537-2995.1978.18278160585.x.
Abstract
Frozen red blood cells, once thawed and washed, must be used within 24 hours or discarded. In this study, three units of blood underwent two freeze-thaw cycles. It was shown that red blood cell survival, ATP, and 2,3-DPG were not adversely effected. The data suggest that previously frozen red blood cells should be refrozen, rather than discarded, if not used within 24 hours of deglycerolization.
摘要
冷冻红细胞一旦解冻并洗涤，必须在24小时内使用，否则应丢弃。在本研究中，三个单位的血液经历了两个冻融循环。结果表明，红细胞存活率、三磷酸腺苷（ATP）和2,3-二磷酸甘油酸（2,3-DPG）均未受到不利影响。数据表明，如果在去甘油化后24小时内未使用，先前冷冻的红细胞应重新冷冻，而不是丢弃。
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