对用于血管修复的斯帕克斯-曼德里尔动脉移植物前体的再审视。——扫描电子显微镜病理学研究

Another look at the Sparks-Mandril arterial graft precursor for vascular repair. - Pathology by scanning electron microscopy.

作者信息

Guidoin R, Noël H P, Marois M, Martin L, Laroche F, Béland L, Côté R, Gosselin C, Descotes J, Chignier E, Blais P

出版信息

Biomater Med Devices Artif Organs. 1980;8(2):145-67. doi: 10.3109/10731198009118977.

DOI:10.3109/10731198009118977

Abstract

The Sparks-Mandril blood vessel precursor system, an autogenous tissue growth-promoting device, in spite of its ingenuity and its surgical elegance, has received only limited usage. At technique for peripheral blood vessels by several authors. In the latter period, this laboratory also undertook similar work. The results of seven implantations in dogs and two in patients are reported here in the context of a program on the evaluation of blood vessel substitutes, their mode of operation and their long term performance. The clinical status and the pathology of the grafts at time of failure were investigated using techniques of scanning electron microscopy. This work confirms the findings of other centres regarding the generally unsatisfactory performance of the Sparks-Mandril system. Possible causes for failure in mandril-formed blood vessels are discussed.

摘要

斯帕克斯 - 曼德里尔血管前体系统是一种自体组织生长促进装置，尽管其设计精巧、手术操作优雅，但使用范围有限。有几位作者提出了一种用于外周血管的技术。在后期，本实验室也开展了类似工作。本文在血管替代物评估、其运作模式及长期性能的项目背景下，报告了在狗身上进行的七次植入和在患者身上进行的两次植入的结果。使用扫描电子显微镜技术研究了移植物在失效时的临床状况和病理情况。这项工作证实了其他中心关于斯帕克斯 - 曼德里尔系统总体性能不尽人意的研究结果。文中讨论了曼德里尔形成的血管失败的可能原因。