Yoshizawa H, O'Brien J P, Smith W T, Trumper M
J Pathol. 1980 Oct;132(2):95-104. doi: 10.1002/path.1711320202.
Thirty lower lumbar intervertebral discs (IVDs) removed for low-back pain were examined. There is a profuse non-myelinated axonal network and abundant free nerve terminals in the outer (lateral) half of the annulus fibrosus. The inner annulus and the nucleus pulposus did not contain nerve terminals. No significant changes in the nerve networks could be demonstrated in degenerate IVDs: in particular, ingrowth of nerve terminals into foci of granulomatous tissue was not seen. Early foci of degeneration are clearly shown by Marshall's silver method for metalophil cells. Mucinous filaments are argyrophilic and can be mistaken for axonal structures in the nucleus pulposus.
对因腰痛而切除的30个下腰椎椎间盘进行了检查。在纤维环外侧半层有丰富的无髓轴突网络和大量游离神经末梢。纤维环内层和髓核不含神经末梢。在退变的椎间盘中未发现神经网络有明显变化：特别是未见到神经末梢长入肉芽肿组织灶。Marshall嗜银细胞染色法能清晰显示早期退变灶。黏液细丝呈嗜银性，在髓核中可被误认为轴突结构。
