一种活疫苗制剂和四种灭活疫苗制剂对猫抵御鹦鹉热衣原体实验性攻击的保护效力比较。
A comparison of the efficacy of a live and four inactivated vaccine preparations for the protection of cats against experimental challenge with Chlamydia psittaci.
作者信息
Shewen P E, Povey R C, Wilson M R
出版信息
Can J Comp Med. 1980 Jul;44(3):244-51.
Abstract
A commercial live feline-chlamydial vaccine and four experimental inactivated preparations were compared on the basis of clinical protection in cats challenged conjunctivally and intranasally with Chlamydia psittaci. Best protection was afforded by the live vaccine. Good results were also obtained using inactivated preparations of a recent feline conjunctival isolate. Protection did not correlate with the development of complement fixing antibodies but may be related to the induction of a cell mediated response as assessed by the lymphocyte blastogenesis test.
摘要
对一种商业性猫衣原体活疫苗和四种实验性灭活制剂进行了比较，比较的依据是用鹦鹉热衣原体对猫进行结膜内和鼻内攻毒后的临床保护情况。活疫苗提供了最佳保护。使用最近从猫结膜分离株制备的灭活制剂也获得了良好结果。保护作用与补体结合抗体的产生无关，但可能与淋巴细胞增殖试验评估的细胞介导反应的诱导有关。
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