Kimbrough R D
J Environ Sci Health B. 1980;15(6):977-92. doi: 10.1080/03601238009372225.
The health effects of two pesticides, chlordimeform and propanil, are discussed. Chlordimeform and 2-methyl-4-chloroaniline, a major metabolite of chlordimeform, cause severe hemorrhagic cystitis in humans. In cats, however, only a mild effect on the bladder was noted. The herbicide propanil has produced chloracne in humans, and along with 3,4-dichloroaniline, hyperkeratosis in rabbits. The contaminants 3,4,3',4'-tetrachloroazobenzene and 3,4,3',4'-tetrachloroazoxybenzene are responsible for the chloracnegenic characteristics of propanil, 3,4-dichloroaniline, and methazole.
讨论了两种农药，即杀虫脒和敌稗的健康影响。杀虫脒及其主要代谢产物2-甲基-4-氯苯胺会导致人类严重的出血性膀胱炎。然而，在猫身上，仅观察到对膀胱有轻微影响。除草剂敌稗会导致人类患氯痤疮，并且与3,4-二氯苯胺一起，会使兔子出现角化过度。污染物3,4,3',4'-四氯偶氮苯和3,4,3',4'-四氯氧化偶氮苯是敌稗、3,4-二氯苯胺和甲草唑产生氯痤疮特性的原因。
